Salivary gland cytology and Milan System in the Oncology and Radiobiology Institute
Keywords:
biopsia aspirativa con aguja fina, neoplasias de glándulas salivales, sensibilidad y especificidadAbstract
Introduction: the Milan System for Reporting Salivary Gland Cytology (MSRSGC) has been validated in several studies and is recognized by the WHO. It fosters better communication between clinicians and institutions, improves reporting standardization, and correlates diagnostic categories with malignancy risk and clinical management strategies.
Objectives: to characterize salivary gland fine needle aspiration biopsy at the Institute of Oncology and Radiobiology based on the application of the MSRSGC. To correlate the results of cytological and histological studies. To establish the sensitivity and specificity of this procedure.
Method: a retrospective, descriptive, and cross-sectional observational study of fine needle aspiration biopsies of salivary gland lesions was conducted between January 1, 2023, and December 31, 2024, and surgical biopsies through April 30, 2025.
Results: a total of 142 punctures were found. 52.84% of the punctured samples were male. The mean age was 63 years. Parotid punctures accounted for 97.18 %. The sample was nondiagnostic in 11.97 %. The most frequently reported category was Milan IVA, with Warthin's tumor being the most frequently diagnosed benign neoplasm. Only 30 patients underwent surgery. The sensitivity and specificity for identifying neoplasia were 80% and 42.85%, respectively, and for identifying malignancy, 87% and 81%, respectively.
Conclusions: the "Milan I: nondiagnostic" category, at 11.97%, was below the desired rate for the SMRCGS. The most frequently diagnosed categories were Milan IVA (benign neoplasia), Milan II (nonneoplastic), and Milan VI (malignant). Sensitivity and specificity in our study were compromised by the small number of cases operated on.
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