Cholangiohepatocarcinoma as a second primary tumor
Abstract
Fundament: Cholangiohepatocarcinoma is considered as an independent entity, they are rare mixed tumors that share characteristics with hepatocellular carcinoma and cholangiocarcinomas Hepatocellular carcinoma is the fourth cause of mortality for cancer around the world; typically it arises at a zone of hepatic chronic inflammation and fibrosis. Cholangiocarcinomas are a group of neoplasms that appear on any part of biliary tract.
Objective: To introduce a clinical case of a Cholangiohepatocarcinoma as a second primary tumor in a patient treated in Oncology Service of III Congreso.
Clinical case: A 68-year-old, male, white patient, who had the diagnosis of epidermoid carcinoma of the larynx on 2006, was treated with Radiotherapy with curative intention. At the present, on medical interview, by a routinely abdominal ultrasound is identified a hepatic tumor that was diagnosed as a cholangiohepatocarcinoma. The patient received surgery and systemic treatment later.
Conclusions: This case record provides information about this neoplasm, because there are few documented and studied cases on our country. Surgery and Later Systemic Treatment are extremely important as therapeutic weapons in this case.
Downloads
References
Vogel A, Meyer T, Sapisochin G, Salem R, Saborowski A. Hepatocellular Carcinoma. The Lancet. 2022; 400(10360): 1345-1362. [Citado 3 Abr 2022]. Disponible en: https://doi.org/10.1016/S0140-6736(22)01200-4
Zakka K, Renjian Jiang et al. Clinical outcomes of rare hepatocellular carcinoma variants compared to pure hepatocellular carcinoma. J Hepatocell Carcinoma. 2019; 6: 119-129. [Citado 3 Abr 2022]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660638
Ventura Y, Carr BI, et al. Analysis of aggressiveness factors in hepatocellular carcinoma patients undergoing transarterial chemoembolization. World J Gastroenterol. 2018 Apr 21; 24(15): 1641-1649. [Citado 3 Abr 2022]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910547
Matilla Peña AM, Clemente Sánchez A, Ramón Botella E, et al. Colangiocarcinoma. Medicine, Programa de Formación Médica Continuada Acreditado, Vol 13, Issue 12, 2020. Pág. 666-677. [Citado 3 Abr 2022]. Disponible en: https://www.sciencedirect.com/science/article/pii/S03045412203001578
D´Alaimo Brenes N, D´Ávanzo Zúñiga D, Mora membreño K, et al. Abordaje del colangiocarcinoma. Revista Médica Sinergia. Vol. 5 No 6, 2020. [Citado 3 Abr 2022]. Disponible en: https://dialnet.uniroja.es/servlet/articulo?codigo=7445655
Pérez Navarro JV, Tello Barba IM, Anaya-Prado R et al. Colangiocarcinoma, una revisión de retos en diagnóstico y manejo. Elsevier Vol. 36. No 1 Pág. 48-57. [Citado 3 Abr 2022]. Disponible en: https://elsevier.es/es-revista-cirujano-general-218-articulo-colangiocarcinoma-una-revision-retos-diagnostico-X1405009914552009
Petrick JL, Thistle JE, et al. Body mass index, diabetes and intrahepatic cholagiocarcinoma risk: the liver cancer pooling project and meta-analysis. Am J Gastroenterol. 2018 Oct; 113 (10):1494-1505. [Citado 3 Abr 2022]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521884
Morales Cruz M, Armillas Canseco F, et al. Valor pronóstico de margen quirúrgico positivo tras la resección de un colangiocarcinoma. Experiencia de un centro de alto volumen en cirugía hepatopancreatobiliar. Revista de Gastroenterología de México 85 (1), 18-24, 2020. [Citado 3 Abr 2022]. Disponible en: https://www.sciencedirect.com/science/article/pii/S2255534X19301185
Banalkes JM, Iñarrairaeigui M, Arbelaiz A et al. Serum metabolites as diagnostic biomarkers for cholangiocarcinoma, hepatocellular carcinoma, and Primary Sclerosing Cholangitis. Hepatology Volume 70, Issue 3, p. 547-562 2018. [Citado 4 Abr 2022]. Disponible en: https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/hep.30319
Holzner ML, Tabrizian Parissa, et al. Resection of Mixed Hepatocellular-Cholangiocarcinoma, Hepatocellular carcinoma, and Intrahepatic Cholangiocarcinoma. Liver transplantation 26 (7), 888-898, 2020. [Citado 3 Abr 2022]. Disponible en: https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/lt.25786
Ramai D, Ofosu A, Lai JK, et al. Combined Hepatocellular-Cholangiocarcinoma: a population-based retrospective study. The American Journal of Gastroenterology. Sept 2019 Vol 114, Issue 9, p.1496-1501. [Citado 4 Abr 2022]. Disponible en: https://journals.lww.com/ajg/Abstract/2019/09000/Combined_Hepatocellular_Cholangiocarcinoma_A.18.aspx
Lin CW, Wu TS, Lin HY et al. Clinical features and outcomes of combined hepatocellular carcinoma and cholangiocarcinoma versus hepatocellular carcinoma versus cholangiocarcinoma after surgical resection: a propensity score matching analysis. BMC Gastroenterol 21, 20 (2021). [Citado 4 Abr 2022]. Disponible en: https://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-020-01586-4
Tang Y, Wang L, Teng Fei et al. The clinical characteristics and prognostic factors of combined hepatocellular carcinoma and cholangiocarcinoma, hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Medicine 98 (38), 2019. [Citado 4 Abr 2022]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756736/
Lo EC, Rucker AN, Federle MP Hepatocellular carcinoma and intrahepatic cholagiocarcinoma: imaging for diagnosis, tumor response to treatment and Liver Response to Radiation. Seminars in Radiation Oncology, Vol 28, Issue 4, 208, p.267-276. [Citado 4 Abr 2022]. Disponible en: https://www.sciencedirect.com/science/article/pii/S1053429618300559
Downloads
Published
How to Cite
Issue
Section
License
Esta revista provee acceso libre e inmediato a su contenido bajo el principio de que hacer disponible gratuitamente la investigación al público apoya a un mayor intercambio de conocimiento global.
Esto significa que se permite su copia y distribución por cualquier medio siempre que mantenga el reconocimiento de sus autores, no haga uso comercial de las obras y no realice ninguna modificación de ellas.
El envío de manuscritos, el procesamiento y la publicación no ofrece ningún coste a los autores, es totalmente gratis.
