Medullary thyroid carcinoma: about a case
Abstract
Medullary thyroid carcinoma (MTC) is a rare malignant neuroendocrine tumor that originates in the parafollicular cells of the thyroid. With the aim of describing the clinical and pathological characteristics of a case of medullary thyroid carcinoma, a 35-year-old female patient is presented with an increase in volume in the left anterior region of the neck, with a six-month evolution. On physical examination, she had a firm, non-tender nodule in the left lobe of the thyroid. Fine-needle aspiration cytology was performed and reported a suspicion of medullary carcinoma. Finally, the diagnosis was confirmed with the biopsy. Medullary carcinomas are rare tumors with nonspecific symptoms and a highly variable cytological and histological appearance. For this reason, it is vital to understand its clinical manifestations and anatomopathological characteristics, which facilitate timely diagnosis and treatment, thereby improving the quality of life for affected patients.
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Herrero-Ruiz A, Sánchez-Marcos AI, Martín-Almendra MA, García-Duque M, Beaulieu-Oriol LM, Mories-Álvarez MT. Diagnóstico del carcinoma medular de tiroides. Rev. ORL. 2022;13(2):181-192. Disponible en: https://doi.org/10.14201/orl.27141
Jaber T, Dadu R, Hu M. Medullary thyroid carcinoma. Curr Opin Endocrinol Diabetes Obes. 2021;28(5):540546. Disponible en: http://dx.doi.org/10.1097/MED.0000000000000662
Cabal-López PD. Carcinoma medular de tiroides metastásico a hígado y pulmón. Paciente asintomática con enfermedad activa. Repert.med.cir. 2011;20(2):124-127.
Román-González A, Jiménez C. Carcinoma medular de tiroides. ResearchGate. 2021. 1877-83
Elizondo Cerdas A. Histopatología del cáncer de tiroides. Revista Médica de Costa Rica y Centroamérica. 2014;(610):253-258.
Fallahi P, Patrizio A, Stoppini G, Elia G, Ragusa F, Paparo SR, et al. Simultaneous Occurrence of Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma: A Case Series with Literature Review. Curr. Oncol. 2023, 30, 10237–10248. Disponible en: https://doi.org/10.3390/curroncol30120745
Morlán Herrador L, de Arriba Antonio, Miguel G, Ferrer M, Labarta JI. Estudio de carcinoma medular de tiroides a partir de un caso índice. Arch Argent Pediatr 2016;114(6):e421-e424.
Puerto Lorenzo JA, Torres Ajá L, Cabanes Rojas E. Carcinoma medular esporádico de tiroides. Revista Cubana de Cirugía. 2021 (Oct-Dic);60(4):e_1067
Jayasinghe R, Basnayake O, Jayarajah U, Seneviratne S. Management of medullary carcinoma of the thyroid: a review. Journal of International Medical Research. 2022;50(7):1–20. Disponible en: http://dx.doi.org/10.1177/03000605221110698
Thomas CM, Asa SL, Ezzat S, Sawka AM, Goldstein D. Diagnosis and pathologic characteristics of medullary thyroid carcinoma—review of current guidelines. Curr Oncol. 2019 October;26(5):338-344.
Poller D, Kerr D,? Lozano M,? Vielh P. Medullary Thyroid Carcinoma. En: Ali S, VanderLaan P, editors. The Bethesda System for Reporting Thyroid Cytopathology. 3ra ed. Suiza: Springer Nature Switzerland AG; 2023. p.177-8.
Tallini G, Giordano T. Thyroid Gland. En: Goldblum J, Lamps L, McKenney J, Myers J, editors. Rosai and Ackerman’s Surgical Pathology, 11na ed. Filadelfia: ELSEVIER; 2018. p. 322-3.
Kumar V, Abbas A, Aster J. Robbins Patología Humana. 10ma ed. Barcelona: ELSEVIER; 2018.
Morales Martín G, Rodríguez Padilla A, Escoresca Suárez I. Carcinoma medular de tiroides: consenso sobre diagnóstico, manejo y tratamiento. Cir Andal. 2020;31(3):236-41. Disponible en: http://dx.doi.org/10.37351/2020313.4
Kazakou P, Simeakis G, Alevizaki M, Saltiki K. Medullary thyroid carcinoma (MTC): unusual metastatic sites. Endocrinlogy Diabetes and Metabolism. 2021;21-0063.
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Copyright (c) 2026 Alejandro Jarol Pavón Rojas, Luvia Ines Vistorte Vistorte, Dainel Antonio Blanco Fernández, Lisvan Cisnero Reyes, Osleidys Rojas Silva
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